Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036135 | 0.80 | HAO1 (0.41) | KDM4ETDP1HPGDKMT2AMEN1 | |
| SCHEMBL8778643 | 0.74 | ALDH1A1 (0.44) | KDM4ETDP1NPSR1L3MBTL1RXFP1 | |
| SCHEMBL15659227 | 0.74 | KDM4E (0.45) | KDM4EHPGDMAPTALDH1A1GLA | |
| SCHEMBL18796102 | 0.72 | HTT (0.61) | KDM4ETDP1NPSR1L3MBTL1RXFP1 | |
| SCHEMBL8778644 | 0.72 | MAPT (0.47) | KDM4ETDP1NPSR1L3MBTL1RXFP1 | |
| SCHEMBL30100747 | 0.72 | KDM4E (0.46) | KDM4ETDP1HPGDKMT2AMAPT | |
| SCHEMBL149537 | 0.72 | KDM4E (0.46) | KDM4ETDP1HPGDKMT2AMAPT | |
| SCHEMBL29666411 | 0.72 | KDM4E (0.46) | KDM4ETDP1HPGDKMT2AMAPT | |
| SCHEMBL4302592 | 0.71 | KDM1A (0.51) | KDM4EL3MBTL1DHFRHPGDKMT2A | |
| SCHEMBL159102 | 0.71 | KDM4E (0.44) | KDM4ETDP1NPSR1L3MBTL1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103232401-B | A kind of synthetic method of 4-arylthio quinazoline compounds | JIANG University OF TECHNOLOGY (CN) | 2015-11-04 | — | — | CN | disclosed |