SCHEMBL28036036

SCHEMBL28036036

CC(=O)c1ccc(Cc2cccc(Cc3ccc(C(C)=O)cc3)c2)cc1

nearest known ligand 0.78

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.78
KMT2A Q03164 1/20 0.76
CYP19A1 P11511 1/20 0.53
PLA2G10 O15496 1/20 0.50
PLA2G2A P14555 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
MAOB P27338 8/20 0.49
MAOA P21397 2/20 0.47
HSD17B10 Q99714 1/20 0.46
MAPT P10636 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45
RXRG P48443 1/20 0.45
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
TSHR P16473 1/20 0.45
HNF4A P41235 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772794 0.88 LMNA (1.00) LMNAKMT2APLA2G10PLA2G2AMAOB
SCHEMBL6859304 0.87 KMT2A (1.00) LMNAKMT2APLA2G10PLA2G2AMAOB
SCHEMBL2610304 0.84 MAOB (0.67) LMNAKMT2AHDAC1HDAC6MAOB
SCHEMBL3335985 0.83 LMNA (0.59) LMNAKMT2AMAOBMAOA
SCHEMBL9474642 0.82 LMNA (0.89) LMNAKMT2APLA2G10PLA2G2AMAOB
SCHEMBL6190226 0.82 LMNA (0.69) LMNAKMT2APLA2G10PLA2G2AMAOB
SCHEMBL11224189 0.79 KMT2A (0.68) LMNAKMT2AMAOBMAOAHSD17B10
SCHEMBL2688501 0.79 KMT2A (0.83) LMNAKMT2AMAOBMAOAHSD17B10
SCHEMBL16864582 0.79 KMT2A (0.83) LMNAKMT2APLA2G10PLA2G2AHSD17B10
SCHEMBL16797208 0.79 KMT2A (0.83) LMNAKMT2AMAOBHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104926698-A Tetradentate beta-diketone ligand-europium fluorescent complex and application thereof DALIAN CHEMICAL PHYSICS INST 2015-09-23 CN disclosed