Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.58 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9474883 | 0.96 | LMNA (0.81) | LMNAKMT2AMAPTSMN1; SMN2PLA2G10 | |
| SCHEMBL2772794 | 0.94 | LMNA (1.00) | LMNAKMT2AMAPTSMN1; SMN2PLA2G10 | |
| SCHEMBL7741913 | 0.89 | MAPT (0.70) | LMNAKMT2AMAPTSMN1; SMN2MAOB | |
| SCHEMBL6859304 | 0.85 | KMT2A (1.00) | LMNAKMT2AMAPTSMN1; SMN2PLA2G10 | |
| SCHEMBL7252924 | 0.83 | MAPT (1.00) | LMNAMAPTSMN1; SMN2HSD17B1HPGD | |
| SCHEMBL51207 | 0.83 | MAPT (1.00) | LMNAMAPTSMN1; SMN2HSD17B1HPGD | |
| SCHEMBL7738989 | 0.83 | MAPT (1.00) | LMNAMAPTSMN1; SMN2HSD17B1HPGD | |
| SCHEMBL28036036 | 0.82 | LMNA (0.78) | LMNAKMT2AMAPTSMN1; SMN2PLA2G10 | |
| SCHEMBL2354530 | 0.82 | LMNA (0.77) | LMNAKMT2AMAPTSMN1; SMN2MAOB | |
| SCHEMBL16864582 | 0.82 | KMT2A (0.83) | LMNAKMT2AMAPTSMN1; SMN2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5112504-A | — | — | None | — | — | JP | disclosed |
| JP-H05112504-A | BUTADIENE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME | MITA IND CO LTD | 1993-05-07 | — | — | JP | disclosed |