Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28324262 | 0.92 | FOLH1 (0.59) | FOLH1CA1CA2CA9ALDH1A1 | |
| Benzene SCHEMBL8597142 | 0.92 | FOLH1 (0.59) | FOLH1CA1CA2CA9ALDH1A1 | |
| SCHEMBL136079 | 0.92 | FOLH1 (0.59) | FOLH1CA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4542361 | 0.90 | FOLH1 (0.57) | FOLH1CA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20641021 | 0.90 | FOLH1 (0.57) | FOLH1CA1CA2CA9ALDH1A1 | |
| SCHEMBL21836661 | 0.90 | FOLH1 (0.57) | FOLH1CA1CA2CA9ALDH1A1 | |
| SCHEMBL27981445 | 0.90 | FOLH1 (0.57) | FOLH1CA1CA2CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28298696 | 0.88 | FOLH1 (0.55) | FOLH1CA1CA2CA9ALDH1A1 | |
| Lactic Acid SCHEMBL28343599 | 0.80 | FOLH1 (0.47) | FOLH1ALDH1A1ALOX15TSHRHMGB1 | |
| Phthalic Acid SCHEMBL3700659 | 0.79 | ALDH1A1 (0.78) | CA1CA2CA9ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037186-A | Preparation method of aminomethylbenzoic acid | SUZHOU JINGYE MEDICINE & CHEMICAL CO LTD | 2015-11-11 | — | — | CN | claimed |
| CN-105929098-A | Aminomethylbenzoic acid and injection composition and quality control method thereof | 湖南洞庭药业股份有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-105037186-A | Preparation method of aminomethylbenzoic acid | SUZHOU JINGYE MEDICINE & CHEMICAL CO LTD | 2015-11-11 | — | — | CN | disclosed |