Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.85 |
| ▸ | CA9 | Q16790 | 17/20 | 0.85 |
| ▸ | CA12 | O43570 | 15/20 | 0.85 |
| ▸ | CA1 | P00915 | 15/20 | 0.85 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.85 |
| ▸ | CA7 | P43166 | 6/20 | 0.85 |
| ▸ | CA6 | P23280 | 5/20 | 0.85 |
| ▸ | CA5A | P35218 | 5/20 | 0.85 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.85 |
| ▸ | CA4 | P22748 | 4/20 | 0.85 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.85 |
| ▸ | TSHR | P16473 | 2/20 | 0.85 |
| ▸ | USP2 | O75604 | 1/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.85 |
| ▸ | CA3 | P07451 | 3/20 | 0.64 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL8449748 | 0.97 | CA2 (0.90) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27545160 | 0.95 | CA2 (0.85) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27440502 | 0.95 | CA2 (0.85) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27352502 | 0.95 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL8380125 | 0.93 | CA2 (0.81) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL27911829 | 0.93 | CA2 (0.81) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL2798899 | 0.92 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL740 | 0.92 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL30659052 | 0.92 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL31544839 | 0.92 | CA2 (1.00) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106535637-A | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | 美国陶氏益农公司 | 2017-03-22 | — | — | CN | claimed |
| CN-110505874-A | Molecule and relative intermediate, composition and method with desinsection effectiveness | DOW AGROSCIENCES LLC | 2019-11-26 | — | — | CN | disclosed |
| CN-110087469-A | Molecule and relative intermediate, composition and method with certain desinsection effectiveness | 美国陶氏益农公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109475126-A | Control the composition and method of spider type guiding principle species fecundity | FMC有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109152360-A | IN SITU TREATMENT OF SEED IN FURROW | FMC有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-109068644-A | Insect repellant | FMC有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108368125-A | Acc inhibitors and uses thereof | 吉利德阿波罗公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108349995-A | Pyrazoles ACC inhibitor and application thereof | 吉利德阿波罗公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108349994-A | Triazole ACC inhibitor and application thereof | 吉利德阿波罗公司 | 2018-07-31 | — | — | CN | disclosed |
| CN-108290902-A | Esters ACC inhibitor and application thereof | 吉利德阿波罗公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107616168-A | Aqueous suspension shape composition pesticide | 日产化学工业株式会社 | 2018-01-23 | — | — | CN | disclosed |
| CN-107372525-A | A kind of Herbicidal combinations of humulone of sulphur containing triazole and its application | 青岛清原化合物有限公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-107108383-A | Nitrification inhibitor composition and process for preparing same | 美国陶氏益农公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-103635089-B | Comprise the reactive compound compound of (sulfur generation) carboxamide derivative and Fungicidal compounds | 拜耳知识产权有限责任公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-105007737-A | 3-alkyl-5-fluoro-4-substituted-imino-3, 4-dihydropyrimidin-2 (1H) -one derivatives as fungicides | DOW AGROSCIENCES LLC | 2015-10-28 | — | — | CN | disclosed |