Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfanilamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 1.00 |
| ▸ | CA9 | Q16790 | 16/20 | 1.00 |
| ▸ | CA12 | O43570 | 14/20 | 1.00 |
| ▸ | CA1 | P00915 | 14/20 | 1.00 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 1.00 |
| ▸ | CA7 | P43166 | 7/20 | 1.00 |
| ▸ | CA6 | P23280 | 5/20 | 1.00 |
| ▸ | CA5A | P35218 | 5/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 1.00 |
| ▸ | CA4 | P22748 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfanilamide SCHEMBL31544839 | 1.00 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL30659052 | 1.00 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL2798899 | 1.00 | CA2 (1.00) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL8828319 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL22501553 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL19210078 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL5894222 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL8030126 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL3273308 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 | |
| Sulfanilamide SCHEMBL1155220 | 0.97 | CA2 (0.94) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 167768 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637602-B2 | Refrigerant compositions and use thereof | MEXICHEM FLUOR S.A. DE C.V. (MX) | 2026-05-26 | — | — | US | claimed |
| CN-116730879-B | Method for selectively synthesizing 4-amino-N- (hetero) aryl sulfonamide compound | SHAANXI NORMAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-117169187-B | Preparation method of surface-enhanced Raman spectrum substrate for detecting residual of polysulfonamides | 江西农业大学 | 2026-05-22 | — | — | CN | claimed |
| WO-2026099533-A1 | TREATMENT OF ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) WITH GPBP1 INHIBITORS | UNIVERSITAT DE VALÈNCIA (ES) | 2026-05-15 | — | — | WO | claimed |
| EP-4740967-A1 | LINKER-DRUG MOLECULE AND ANTIBODY DRUG CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Escugen Biotechnology Co., Ltd. (CN) | 2026-05-13 | — | — | EP | claimed |
| CN-122010656-A | Application of oxyalkylisourea in introducing methyl and isotopically-labeled methyl | 陕西师范大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4474064-B1 | FIN AND TUBE TYPE AND MICROCHANNEL TYPE HEAT EXCHANGERS AND MANUFACTURING METHOD THEREOF. | LG ELECTRONICS INC (KR) | 2026-04-29 | — | — | EP | claimed |
| EP-4722232-A1 | SINGLE-CHAIN POLYPEPTIDE ACTIVATED IN USE | YSTE (Hainan) Aesthetic Medicine Health Technology Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| US-20260091119-A1 | ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA | CELLIS AG (CH) | 2026-04-02 | — | — | US | claimed |
| US-20260086084-A1 | TEST STRIP ASSEMBLY FOR ANALYSING BODILY FLUIDS AND DEVICES THEREOF | INITO HEALTH INC (US) | 2026-03-26 | — | — | US | claimed |
| US-3985718-A | AN OXIDIZING AGENT, A CHELATE COMPOUND, AN ELECTRON DONOR AND A CHELATING COMPLEX | RHONE-POULENC S.A. (FR) | 1976-10-12 | — | — | US | claimed |
| US-3981869-A | BENZOTHIAZOLE, BENZOXAZOLE AND INDOLE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | claimed |
| US-3980427-A | MONOAZO OR DISAZO DYE, HALOGENATED HYDROCARBON | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | claimed |
| US-3975399-A | PROSTAGLANDIN LIKE ACTIVITY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | claimed |
| US-3969198-A | NICKEL, IRON, ELECTROLYTE | PERMALITE CHEMICALS LTD. (EN) | 1976-07-13 | — | — | US | claimed |
| US-3966706-A | 2,6-Dihydroxy-3-cyano-4-methylpyridine containing azo dyes which contain a functional amino group | CIBA-GEIGY AG (CH) | 1976-06-29 | — | — | US | claimed |
| US-3956385-A | REACTING SULFONYLHALIDE WITH 2-CHLORO-ETHYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-05-11 | — | — | US | claimed |
| US-3954796-A | Tetra-(alkylsulphamoyl)-copper phthalocyanines and a process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1976-05-04 | — | — | US | claimed |
| US-3941765-A | Process for the manufacture of symmetric 1:2 chromium complexes of azo dyes | CIBA-GEIGY AG (CH) | 1976-03-02 | — | — | US | claimed |
| US-3933803-A | ANTIBACTERIAL, ANTIMITOTIC, ANTIMYCOTIC | INSTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1976-01-20 | — | — | US | claimed |