Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036404 | 0.91 | TYR (0.49) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL28036390 | 0.87 | KDM4E (0.48) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL2867827 | 0.83 | PRKCI (0.45) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL982658 | 0.81 | KDM4E (0.38) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL983636 | 0.81 | IAPP (0.41) | KDM4EGAANPSR1HSD17B10MAPK1 | |
| SCHEMBL981690 | 0.81 | LTA4H (0.41) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL983363 | 0.80 | TYR (0.43) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL2865457 | 0.79 | KDM4E (0.51) | MEN1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL8022512 | 0.79 | LTA4H (0.42) | MEN1MAPTKMT2AKDM4EGAA | |
| SCHEMBL2352866 | 0.79 | TYR (0.45) | MEN1LMNAMAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102422-A | Method for producing isocyanate | ASAHI KASEI CHEMICALS CORP | 2015-11-25 | — | — | CN | disclosed |