Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984134 | 0.86 | L3MBTL1 (0.53) | POLBL3MBTL1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9095004 | 0.84 | KMT2A (0.52) | POLBL3MBTL1MAPTKMT2ANPC1 | |
| SCHEMBL11705096 | 0.83 | SCN1A (0.33) | POLBL3MBTL1SCN1ASCN2ASCN3A | |
| SCHEMBL3761921 | 0.82 | EPHX2 (0.58) | L3MBTL1EPHX2MAPTGAAHDAC8 | |
| SCHEMBL891250 | 0.81 | CA1 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7528436 | 0.81 | TDP1 (0.37) | L3MBTL1SCN1ASCN2ASCN3AEPHX2 | |
| SCHEMBL7653975 | 0.81 | ALB (0.33) | L3MBTL1SCN1ASCN2ASCN3AEPHX2 | |
| SCHEMBL7648764 | 0.81 | JAK3 (0.37) | KDM1ASCN1ASCN2ASCN3AEPHX2 | |
| SCHEMBL2658831 | 0.81 | ALDH1A1 (0.47) | POLBMAPTKMT2ANPC1RAB9A | |
| SCHEMBL1133942 | 0.81 | MAPT (0.47) | POLBL3MBTL1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142634-A | Oxindole carboxylic acid-based inhibitors of oncogenic protein tyrosine phosphatase-2 (SHP2) comprising Src homology-2 domain | UNIV INDIANA RES & TECH CORP | 2015-12-09 | — | — | CN | disclosed |