Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 4/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743650 | 0.89 | SLC6A3 (0.43) | SLC6A3P2RX7 | |
| SCHEMBL28036226 | 0.88 | SLC6A3 (0.35) | SLC6A3CTSAACP3AOC3 | |
| SCHEMBL28036224 | 0.88 | SLC6A3 (0.35) | SLC6A3CTSACYP19A1AOC3P2RX7 | |
| SCHEMBL28036227 | 0.85 | SLC6A3 (0.34) | SLC6A3SRC | |
| SCHEMBL27743428 | 0.82 | NAMPT (0.37) | SLC6A3 | |
| SCHEMBL27764214 | 0.80 | SLC6A3 (0.33) | SLC6A3 | |
| SCHEMBL27743460 | 0.80 | SLC6A3 (0.33) | SLC6A3P2RX7 | |
| SCHEMBL27741460 | 0.80 | LY96 (0.34) | SLC6A3SRC | |
| SCHEMBL28036654 | 0.79 | SLC6A3 (0.36) | SLC6A3CYP19A1MAPT | |
| SCHEMBL28036658 | 0.79 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017242-A | Novel biphenyl heterocyclic derivative, preparation method and use thereof as drug | UNIV CHINA PHARMA | 2015-11-04 | — | — | CN | disclosed |