SCHEMBL28036668

SCHEMBL28036668

CC(C)COCC(C)C.Fc1cc(F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
PTPN1 P18031 1/20 0.32
TSHR P16473 1/20 0.31
DPP4 P27487 1/20 0.31
CYP3A4 P08684 1/20 0.31
KAT6A Q92794 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19795471 0.82 PTPN1 (0.37) ALDH1A1KDM4EMAPTHTTPTPN1
SCHEMBL19795476 0.82 PTPN1 (0.40) KDM4EMAPTHTTPTPN1DPP4
SCHEMBL19795484 0.81 PTPN1 (0.39) ALDH1A1KDM4EMAPTHTTPTPN1
SCHEMBL22114301 0.77 MAPT (0.38) ALDH1A1KDM4EMAPTHTTCYP3A4
SCHEMBL4737611 0.76 MAPT (0.46) ALDH1A1KDM4EMAPTHTTKAT6A
SCHEMBL19795481 0.73 MAOB (0.40) ALDH1A1KDM4EMAPTHTTTSHR
SCHEMBL19795499 0.72 TSHR (0.49) ALDH1A1KDM4EMAPTHTTTSHR
SCHEMBL19795479 0.72 DPP4 (0.44) KDM4EMAPTHTTPTPN1DPP4
Methoxymethane SCHEMBL27756535 0.72 CA1 (0.36) ALDH1A1MAPTHTT
SCHEMBL19795498 0.71 TSHR (0.47) ALDH1A1KDM4EMAPTHTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105016983-A Preparation method of pentafluorophenol KINGCHEM LIAONING CHEMICAL CO LTD 2015-11-04 CN disclosed