Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27945379 | 1.00 | KDM1A (0.35) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL28413151 | 0.78 | KDM1A (0.42) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL29962540 | 0.78 | KDM1A (0.42) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL8986269 | 0.75 | KDM1A (0.36) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL28018299 | 0.75 | KDM1A (0.38) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL30874319 | 0.75 | KDM1A (0.38) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL27425145 | 0.75 | KDM1A (0.38) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL31249470 | 0.73 | — | — | |
| SCHEMBL7088421 | 0.72 | KDM1A (0.36) | KDM1ALMNAMAPTRAB9AMEN1 | |
| SCHEMBL5565774 | 0.72 | KDM1A (0.33) | KDM1ALMNAMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017041-A | Dibenzosuberan enone derivatives and preparation method therefor and application thereof | UNIV BEIJING SCIENCE & TECH | 2015-11-04 | — | — | CN | disclosed |