SCHEMBL27425145

SCHEMBL27425145

N=C1C=CC=CC1C=Cc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.38
MAOB P27338 1/20 0.35
LMNA P02545 3/20 0.34
MAPT P10636 3/20 0.34
HDAC3 O15379 1/20 0.34
TNKS O95271 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HCAR2 Q8TDS4 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
HDAC9 Q9UKV0 1/20 0.34
HDAC5 Q9UQL6 1/20 0.34
PLIN1 O60240 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30874319 1.00 KDM1A (0.38) KDM1AMAOBLMNAMAPTHDAC3
SCHEMBL27882346 0.92 LMNA (0.36) KDM1AMAOBLMNAMAPTHDAC3
SCHEMBL27919393 0.92 MAPT (0.37) KDM1AMAOBLMNAMAPTHDAC3
SCHEMBL29962540 0.79 KDM1A (0.42) KDM1AMAOBLMNAMAPTHDAC3
SCHEMBL28413151 0.79 KDM1A (0.42) KDM1AMAOBLMNAMAPTHDAC3
SCHEMBL28018299 0.79 KDM1A (0.38) KDM1AMAOBLMNAMAPTALDH1A1
SCHEMBL8986269 0.76 KDM1A (0.36) KDM1AMAOBLMNAMAPTHDAC3
SCHEMBL7088421 0.76 KDM1A (0.36) KDM1AMAOBLMNAMAPTALDH1A1
SCHEMBL3874572 0.75 KDM1A (0.35) KDM1AMAOBLMNAMAPTRAB9A
SCHEMBL8830381 0.75 KDM1A (0.35) KDM1AMAOBLMNAMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC BUCK INST RES AGING (US) 2024-07-04 US disclosed
CN-111999500-B Carbamazepine detection kit 北京九强生物技术股份有限公司 2023-04-18 CN disclosed
CN-115724800-A Method for synthesizing iminostilbene 浙江工业大学 2023-03-03 CN disclosed
CN-112457253-A Method for synthesizing iminostilbene 浙江工业大学 2021-03-09 CN disclosed
CN-111999500-A Carbamazepine detection kit 北京九强生物技术股份有限公司 2020-11-27 CN disclosed
CN-110078711-B Carbamazepine derivative and application thereof in immunodetection 北京九强生物技术股份有限公司 2020-09-18 CN disclosed
CN-104159922-B Enhancement of transport of therapeutic molecules across the blood brain barrier 比奥根MA公司 2018-03-02 CN disclosed
CN-102318100-B Liquid composition for ink-jet printing or other uses of organic layers UNIVERSAL DISPLAY CORP. (US) 2015-09-23 CN disclosed
CN-104916778-A Liquid compositions for inkjet printing of organic layers or other uses UNIVERSAL DISPLAY CORP 2015-09-16 CN disclosed
CN-104159922-A Enhancement of transport of therapeutic molecules across the blood brain barrier BIOGEN IDEC INC 2014-11-19 CN disclosed
CN-102432539-A Crystallization separation method for producing iminostilbene by catalytic dehydrogenation of iminodibenzyl UNIV EAST CHINA SCIENCE & TECH 2012-05-02 CN disclosed
CN-102432538-A Integrated industrial production method for producing iminostilbene by continuous catalytic deamination and catalytic dehydrogenation of 2, 2' -diaminobibenzyl UNIV EAST CHINA SCIENCE & TECH 2012-05-02 CN disclosed
CN-102318100-A Liquid composition for ink-jet printing or other uses of organic layers UNIVERSAL DISPLAY CORP 2012-01-11 CN disclosed
CN-102120729-A Industrial method for producing iminostilbene through catalytic dehydrogenation of iminodibenzyl UNIV EAST CHINA SCIENCE & TECH 2011-07-13 CN disclosed
CN-102077381-A Cross linkable ionic dopants UNIVERSAL DISPLAY CORP 2011-05-25 CN disclosed
CN-101460145-A Antidepressant composition wafer LOHMANN THERAPIE SYST LTS (DE) 2009-06-17 CN disclosed
CN-1136309-C Reduction of malodour ŵ����÷�����޹�˾ 2004-01-28 CN disclosed
CN-1087738-C Method for purifying 5H-dipheyl [6,f] azepine LINZ CHEMICAL CO ITD (AT) 2002-07-17 CN disclosed
CN-1269828-A Reduction of malodour NOVO NORDISK AS (DK) 2000-10-11 CN disclosed
CN-1135482-A Method for purifying 5H-dipheyl [6,f] azepine CHEMIE LINZ GMBH (AT) 1996-11-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216316-A1 DIHOMO-GAMMA LINOLENIC ACID (DGLA) IS A NOVEL SENOLYTIC DAGLA, DAGLB, MGLL KDM1A 2417/4885MAOB 2579/4885LMNA 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.