SCHEMBL28036717

SCHEMBL28036717

NOC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.59
PDCD1 Q15116 1/20 0.58
CD274 Q9NZQ7 1/20 0.58
SMN1; SMN2 Q16637 5/20 0.55
SLC1A5 Q15758 1/20 0.54
MAPT P10636 2/20 0.54
RAB9A P51151 3/20 0.50
NPC1 O15118 2/20 0.50
SCN1A P35498 1/20 0.50
SCN2A Q99250 1/20 0.50
SCN3A Q9NY46 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
EGFR P00533 1/20 0.49
PTPN1 P18031 2/20 0.48
GSK3B P49841 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
WDR5 P61964 1/20 0.48
LMNA P02545 2/20 0.48
F2 P00734 1/20 0.48
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL4259209 0.92 KDM4E (0.53) KDM4EPDCD1CD274SMN1; SMN2SLC1A5
SCHEMBL13310823 0.91 CA12 (0.47) KDM4EPDCD1CD274SMN1; SMN2SLC1A5
SCHEMBL15120801 0.87 BCL2L1 (0.54) KDM4EPDCD1CD274EGFR
SCHEMBL72340 0.86 LMNA (0.64) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA
SCHEMBL9138584 0.84 LMNA (0.61) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA
Hydroxyamine SCHEMBL9520402 0.84 LMNA (0.61) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA
SCHEMBL29171336 0.84 LMNA (0.61) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA
SCHEMBL21585876 0.84 LMNA (0.61) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA
Hydrochloric Acid SCHEMBL5413799 0.84 LMNA (0.61) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA
SCHEMBL28300431 0.84 LMNA (0.61) KDM4ESMN1; SMN2MAPTL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105120978-B Electret webs with charge-enhancing additives 3M创新有限公司 2017-04-05 CN claimed
CN-105120978-A Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES CO 2015-12-02 CN claimed
CN-105120978-B Electret webs with charge-enhancing additives 3M创新有限公司 2017-04-05 CN disclosed
CN-105120978-A Electret webs with charge-enhancing additives 3M INNOVATIVE PROPERTIES CO 2015-12-02 CN disclosed