Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023761 | 0.86 | TLR7 (0.50) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| Hydrochloric Acid SCHEMBL3231113 | 0.84 | TLR7 (0.49) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL14964747 | 0.83 | KMT2A (0.55) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL148103 | 0.81 | DCPS (0.57) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL30689003 | 0.81 | TLR8 (0.51) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| Hydrochloric Acid SCHEMBL6017885 | 0.80 | CYP1A1 (0.58) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL2586754 | 0.79 | TLR8 (0.52) | DCPSCYP1A1CYP1A2CYP1B1RAB9A | |
| SCHEMBL6380647 | 0.78 | TLR7 (0.45) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| SCHEMBL10972564 | 0.76 | DCPS (0.47) | DCPSCYP1A1CYP1A2CYP1B1APP | |
| Hydrochloric Acid SCHEMBL6908984 | 0.76 | NCF1 (0.59) | DCPSCYP1A1CYP1A2CYP1B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112915092-A | Combinations of AKT inhibitor compounds and abiraterone and methods of use | 基因泰克公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-111643504-A | Combinations of AKT inhibitor compounds and chemotherapeutic agents and methods of use | 基因泰克公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-101939006-B | Phosphoinositide 3-kinase inhibitor compounds is combined and using method with chemotherapeutics | GENENTECH, INC. (US) | 2015-09-16 | — | — | CN | disclosed |