Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316024 | 0.87 | KMT2A (0.50) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL6623848 | 0.83 | BCAT2 (0.55) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL1147544 | 0.83 | MAPT (0.50) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL11395216 | 0.81 | KMT2A (0.45) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL3321379 | 0.79 | KDM4E (0.56) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL8109419 | 0.78 | BCAT2 (0.44) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL4673228 | 0.76 | KMT2A (0.42) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL3609310 | 0.75 | TSHR (0.58) | ALOX15TP53MAPK1LMNAALDH1A1 | |
| SCHEMBL27470372 | 0.74 | NPC1 (0.49) | KMT2AALOX15TP53MAPK1LMNA | |
| SCHEMBL22157985 | 0.73 | TP53 (0.44) | KMT2AALOX15TP53MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037115-B | synthetic method of diaryl ketone compound | 浙江工业大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-104987273-B | catalytic oxidation synthesis method of diaryl ketone compound | 浙江工业大学 | 2016-08-24 | — | — | CN | disclosed |
| CN-105037115-A | synthetic method of diaryl ketone compound | UNIV ZHEJIANG TECHNOLOGY | 2015-11-11 | — | — | CN | disclosed |
| CN-104987273-A | Catalytic oxidation synthesis method of diaryl ketone compound | UNIV ZHEJIANG TECHNOLOGY | 2015-10-21 | — | — | CN | disclosed |