Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 2/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623848 | 0.82 | BCAT2 (0.55) | BCAT2KMT2AMAPK1TP53ALOX15 | |
| SCHEMBL28036792 | 0.78 | KMT2A (0.50) | BCAT2KMT2AMAPK1TP53ALOX15 | |
| SCHEMBL3316024 | 0.78 | KMT2A (0.50) | BCAT2KMT2AMAPK1TP53ALOX15 | |
| SCHEMBL11395216 | 0.76 | KMT2A (0.45) | BCAT2KMT2AMAPK1TP53ALOX15 | |
| SCHEMBL1147544 | 0.74 | MAPT (0.50) | BCAT2KMT2AMAPK1TP53ALOX15 | |
| Bicarbonate SCHEMBL28388818 | 0.72 | F2 (0.52) | BCAT2WDR5KMT2AALOX15ALDH1A1 | |
| SCHEMBL6588159 | 0.72 | IKBKB (0.51) | BCAT2KMT2AMAPK1MEN1ALDH1A1 | |
| SCHEMBL10495281 | 0.71 | F2 (0.55) | WDR5KMT2AALOX15ALDH1A1LMNA | |
| SCHEMBL3321379 | 0.70 | KDM4E (0.56) | KMT2AMAPK1TP53ALOX15MEN1 | |
| SCHEMBL8084435 | 0.69 | BCAT2 (0.68) | BCAT2WDR5KMT2ANQO2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020488-A | Small molecule inhibition of RNA/ligand binding | SCRIPTGEN PHARMACEUTICALS INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0833824-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5668165-A | TREATMENT OF HIV INFECTIONS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996040668-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |