Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 5/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987125 | 0.84 | ESR2 (0.46) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL10600837 | 0.79 | ESR1 (0.63) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL1856265 | 0.78 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL28873677 | 0.78 | LOXL2 (0.52) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL27915409 | 0.77 | LOXL2 (0.50) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7863498 | 0.77 | TAAR1 (0.50) | ESR2ESR1TAAR1 | |
| SCHEMBL27537686 | 0.75 | LOXL2 (0.48) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL28145561 | 0.71 | LOXL2 (0.44) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL28494873 | 0.69 | PNMT (0.41) | MEN1ALDH1A1KMT2ATAAR1 | |
| SCHEMBL28748834 | 0.69 | SLC6A2 (0.41) | KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037273-A | Diaryl hydantoin compound | UNIV CALIFORNIA | 2015-11-11 | — | — | CN | disclosed |