Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13557773 | 0.86 | CYP19A1 (0.55) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL22303441 | 0.83 | CYP19A1 (0.52) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL27888098 | 0.83 | CYP19A1 (0.52) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL7068828 | 0.81 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP1A2KIF11CYP3A5 | |
| SCHEMBL29387897 | 0.81 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP1A2KIF11CYP3A5 | |
| SCHEMBL29583584 | 0.81 | KIF11 (0.61) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL74389 | 0.81 | KIF11 (0.61) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| SCHEMBL13577 | 0.81 | CYP19A1 (0.57) | CYP19A1CYP3A4CYP1A2KIF11CYP3A5 | |
| SCHEMBL10044245 | 0.79 | CYP19A1 (0.49) | CYP19A1CYP3A4LMNACYP1A2CYP11B1 | |
| Hydrochloric Acid SCHEMBL21796041 | 0.79 | CYP19A1 (0.55) | CYP19A1CYP3A4KIF11CYP3A5KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103237800-B | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-10-21 | — | — | CN | disclosed |