SCHEMBL74389

SCHEMBL74389

CC(C)(C)c1cccnc1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.61
CYP19A1 P11511 5/20 0.59
LMNA P02545 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP11B1 P15538 1/20 0.53
CYP11B2 P19099 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 2/20 0.46
THRB P10828 1/20 0.46
POLB P06746 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29583584 1.00 KIF11 (0.61) KIF11CYP19A1LMNACYP1A2CYP3A4
Boric Acid SCHEMBL29093528 0.91 KIF11 (0.53) KIF11CYP19A1LMNACYP1A2CYP3A4
3-Methylpyridine SCHEMBL27533699 0.89 KIF11 (0.52) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL2272647 0.86 LMNA (0.56) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL27996644 0.83 CYP19A1 (0.57) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL23059263 0.81 CYP19A1 (0.55) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL9547408 0.81 CYP19A1 (0.55) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL13557773 0.81 CYP19A1 (0.55) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL11623047 0.81 CYP19A1 (0.60) KIF11CYP19A1LMNACYP1A2CYP3A4
SCHEMBL19229667 0.81 CYP19A1 (0.55) KIF11CYP19A1LMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3924 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118496414-A Preparation method of ultrahigh molecular weight cationic polyacrylamide and solvent synergistic initiator thereof 四川大学 2024-08-16 CN claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-116056532-A Preparation method of perovskite film 安徽科技学院 2023-05-02 CN claimed
CN-115915781-A Perovskite solar cell and preparation method thereof 安徽科技学院 2023-04-04 CN claimed
CN-112094300-A Dicyano tetra-tert-butyl pyridine ruthenium metal organic compound, preparation method and application thereof 荆楚理工学院 2020-12-18 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
US-8697820-B2 Process for preparing high-reactivity isobutene homo- or copolymers BASF SE (DE) 2014-04-15 US claimed
EP-4318630-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS SECONDARY BATTERY ASAHI CHEMICAL IND (JP) 2025-10-22 EP disclosed
US-20250122323-A1 ONIUM SALT, BLOCKING AGENT DISSOCIATION CATALYST FOR BLOCKED ISOCYANATE, BLOCKED ISOCYANTE COMPOSITION INCLUDING BLOCKING AGENT DISSOCIATION CATALYST, THERMOSETTING RESIN COMPOSITION, AND CURED PRODUCT AND MANUFACTURING METHOD THEREFOR KOEI CHEMICAL COMPANY, LIMITED (JP) 2025-04-17 US disclosed
CN-119731596-A Photosensitive resin composition, photosensitive resin sheet, cured product, method for producing cured product, semiconductor device, display device, and method for producing resin 东丽株式会社 2025-03-28 CN disclosed
US-12199280-B2 Non-aqueous secondary battery and non-aqueous electrolyte ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-01-14 US disclosed
EP-4472968-A1 INHIBITORS OF RAF KINASES PIERRE FABRE MEDICAMENT (FR) 2024-12-11 EP disclosed
CN-118496414-A Preparation method of ultrahigh molecular weight cationic polyacrylamide and solvent synergistic initiator thereof 四川大学 2024-08-16 CN disclosed
US-6680324-B2 4-AMINO-6-PHENYL-PYRROLO(2,3-D)PYRIMIDINE DERIVATIVES OSI PHARMACEUTICALS, INC. 2004-01-20 US disclosed
EP-0985674-B1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR ALPHA-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING ALPHA-OLEFIN POLYMERS MITSUBISHI CHEM CORP (JP) 2003-04-23 EP disclosed
US-6255515-B1 COORDINATION POLYMERIZATION CATALYSTS MITSUBISHI CHEMICAL CORPORATION (JP) 2001-07-03 US disclosed
EP-0985674-A1 ORGANIC COMPOUNDS CONTAINING SILICON OR GERMANIUM, TRANSITION METAL COMPLEXES, CATALYST FOR $g(a)-OLEFIN POLYMERIZATION, AND PROCESSES FOR PRODUCING $g(a)-OLEFIN POLYMERS MITSUBISHI CHEMICAL CORPORATION (JP) 2000-03-15 EP disclosed
US-4370507-A RHODIUM-IRON CATALYSTS, HETEROCYCLIC AMINE PROMOTER ETHYL CORPORATION (US) 1983-01-25 US disclosed
US-4361499-A RHODIUM AND IRON ETHYL CORPORATION (US) 1982-11-30 US disclosed
US-3935228-A HYDROESTERIFICATION CATALYST ETHYL CORPORATION (US) 1976-01-27 US disclosed