Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826286 | 0.75 | LMNA (0.37) | LMNATHRBCYP2C19KMT2ACA1 | |
| SCHEMBL9953609 | 0.73 | LMNA (0.40) | LMNATHRBCYP2C19KMT2ACA1 | |
| SCHEMBL2283075 | 0.66 | LMNA (0.45) | LMNATHRBCYP2C19KMT2ACA1 | |
| Methyl Alcohol SCHEMBL27771562 | 0.66 | KMT2A (0.44) | LMNATHRBCYP2C19KMT2ACA1 | |
| SCHEMBL27495941 | 0.66 | ESR1 (0.44) | — | |
| SCHEMBL17635577 | 0.65 | — | — | |
| SCHEMBL6131634 | 0.65 | — | — | |
| SCHEMBL6236180 | 0.65 | — | — | |
| SCHEMBL3955047 | 0.65 | — | — | |
| SCHEMBL4262422 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109200031-A | The method for treating melanoma | 阿布拉科斯生物科学有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-105120859-B | Method for treating melanoma | 阿布拉科斯生物科学有限公司 | 2018-10-09 | — | — | CN | disclosed |
| CN-105120859-A | Method for treating melanoma | ABRAXIS BIOSCIENCE LLC | 2015-12-02 | — | — | CN | disclosed |