Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 16/20 | 0.56 |
| ▸ | KDM1B | Q8NB78 | 6/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6906698 | 0.84 | KDM1A (0.56) | KDM1AKDM1BHTR2AHTR2CHTR2B | |
| SCHEMBL6319144 | 0.77 | KDM1A (0.36) | KDM1AKDM1BKCNH2HTR2AHTR2C | |
| SCHEMBL19452862 | 0.76 | CCNT1 (0.42) | KDM1AHTR2CMAOAADRA1A | |
| SCHEMBL12994249 | 0.76 | HTR2C (0.41) | KDM1AHTR2CADRA1A | |
| SCHEMBL8884797 | 0.75 | KDM1A (0.66) | KDM1AKDM1BKCNH2HTR2CHTR2B | |
| SCHEMBL6327503 | 0.73 | HTR2C (0.42) | KCNH2HTR2AHTR2CHTR2B | |
| SCHEMBL15682035 | 0.73 | CA2 (0.47) | ADRA1A | |
| SCHEMBL6320155 | 0.72 | ITGB3 (0.49) | HTR2AHTR2CHTR2B | |
| SCHEMBL19452846 | 0.72 | CCNT1 (0.40) | KDM1AHTR2CADRA1A | |
| SCHEMBL13821364 | 0.72 | PDE5A (0.33) | KDM1AHTR2AHTR2CHTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121429-A | Complement pathway modulators and uses thereof | NOVARTIS AG | 2015-12-02 | — | — | CN | disclosed |