Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28037069

N.NCCc1cn(O)c2ccccc12

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.62
HTR6 P50406 16/20 0.51
SCN9A Q15858 1/20 0.49
TAAR1 Q96RJ0 1/20 0.41
OPRM1 P35372 1/20 0.40
OPRK1 P41145 1/20 0.40
OPRL1 P41146 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106451 0.98 HTR2A (0.64) HTR2AHTR6SCN9ATAAR1OPRM1
Hydrochloric Acid SCHEMBL9695585 0.96 HTR2A (0.62) HTR2AHTR6SCN9ATAAR1OPRM1
Carbamic Acid SCHEMBL28875082 0.90 HTR2A (0.55) HTR2AHTR6SCN9A
Fumaric Acid SCHEMBL6273999 0.86 HTR2A (0.51) HTR2AHTR6SCN9A
SCHEMBL20674511 0.79 GPR84 (0.44) HTR2AOPRM1OPRL1
SCHEMBL7561915 0.78 HTR2A (0.66) HTR2AHTR6SCN9ATAAR1
Serotonin SCHEMBL14991266 0.78 HTR2C (0.67) HTR2AHTR6TAAR1
SCHEMBL7037223 0.77 HTR2A (0.60) HTR2AHTR6SCN9A
SCHEMBL25166949 0.76 HTR2A (0.64) HTR2AHTR6SCN9ATAAR1OPRM1
SCHEMBL6787250 0.76 HTR2A (0.64) HTR2AHTR6SCN9ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104936584-B Composition for the prevention and treatment of behavior, spirit and cognitive disorder 瓦伦塔有限责任公司 2017-12-15 CN disclosed
CN-104936584-A Combination for the prophylaxis and treatment of behavioural, mental and cognitive disorders VALENTA INTELLEKT LTD 2015-09-23 CN disclosed