SCHEMBL7561915

SCHEMBL7561915

NCCc1cn(N)c2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.66
HTR6 P50406 16/20 0.54
SCN9A Q15858 1/20 0.51
HRH1 P35367 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27595960 0.85 HTR6 (0.51) HTR2AHTR6SCN9A
SCHEMBL6787250 0.83 HTR2A (0.64) HTR2AHTR6SCN9AHRH1TAAR1
Hydrochloric Acid SCHEMBL25287442 0.81 HTR2A (0.62) HTR2AHTR6SCN9AHRH1
SCHEMBL12410931 0.80 GPR84 (0.42) HTR2AHTR6SCN9A
SCHEMBL10923948 0.79 HTR2A (0.64) HTR2AHTR6SCN9ATAAR1
SCHEMBL106451 0.79 HTR2A (0.64) HTR2AHTR6SCN9ATAAR1
SCHEMBL25166949 0.79 HTR2A (0.64) HTR2AHTR6SCN9ATAAR1
SCHEMBL332959 0.79 HTR2A (1.00) HTR2AHTR6SCN9A
SCHEMBL7928211 0.79 HTR2A (0.58) HTR2AHTR6SCN9AHRH1TAAR1
SCHEMBL7928184 0.79 HTR2A (0.58) HTR2AHTR6SCN9AHRH1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240417764-A1 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY 2024-12-19 US disclosed
EP-4426676-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-09-11 EP disclosed
WO-2023081837-A9 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2024-03-14 WO disclosed
WO-2023081837-A2 METHODS FOR THE PRODUCTION OF TRYPTOPHANS, TRYPTAMINES, INTERMEDIATES, SIDE PRODUCTS AND DERIVATIVES MIAMI UNIVERSITY (US) 2023-05-11 WO disclosed
CN-102802645-B Adsorption test method of spherical carbon adsorbent MITSUBISHI TANABE PHARMA CORP 2014-05-07 CN disclosed
CN-102802645-A Adsorption test method of spherical carbon adsorbent MITSUBISHI TANABE PHARMA CORP 2012-11-28 CN disclosed
CN-1898201-A Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents SENTION INC (US) 2007-01-17 CN disclosed
CN-1610547-A N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor LILLY CO ELI (US) 2005-04-27 CN disclosed
WO-2002064825-A2 MICROELECTRONIC ARRAY DEVICES TO PERFORM MULTIPLEX IMMUNOASSAY ANALYSIS NANOGEN RECOGNOMICS GMBH (DE) 2002-08-22 WO disclosed
US-20010049111-A1 Methods, procedures, and formats for using microelectronic array devices to perform multiplex immunoassay analyses NANOGEN RECOGNOMICS GMBH (DE) 2001-12-06 US disclosed
WO-1995025514-A1 COMPOUNDS USEFUL AS ANXIOLYTIC, SEDATIVE, AND HYPNOTIC AGENTS DISCOVERY THERAPEUTICS, INC. (US) 1995-09-28 WO disclosed