Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27574327 | 0.79 | LOXL2 (0.45) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| SCHEMBL28312818 | 0.76 | ADORA1 (0.49) | — | |
| SCHEMBL543734 | 0.75 | ADORA1 (0.47) | SMN1; SMN2 | |
| SCHEMBL28242972 | 0.73 | ADRB2 (0.59) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| SCHEMBL15110380 | 0.70 | VHL (0.57) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| Hydrochloric Acid SCHEMBL21070735 | 0.69 | VHL (0.56) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| Hydrochloric Acid SCHEMBL26909801 | 0.69 | VHL (0.56) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| SCHEMBL2274647 | 0.68 | HRH3 (1.00) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| SCHEMBL16298860 | 0.68 | HRH3 (0.52) | LOXL2HRH3ADRB2LTA4HTAAR1 | |
| SCHEMBL25592519 | 0.68 | LOXL2 (0.45) | LOXL2HRH3ADRB2LTA4HTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910095-B | The preparation method of 4-replacement-thiazolamine compound | 浙江大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-104910095-A | Preparation method of 4-substituted-2-aminothiazole compound | UNIV ZHEJIANG | 2015-09-16 | — | — | CN | disclosed |