SCHEMBL28037084

SCHEMBL28037084

C[S+]([O-])c1ccc(-c2ncc(-c3ccncc3)n2-c2ccc(F)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.46
MAPK14 Q16539 2/20 0.42
FLT3 P36888 1/20 0.41
ALDH1A1 P00352 2/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP17A1 P05093 1/20 0.37
AOC3 Q16853 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
MLYCD O95822 1/20 0.36
KDR P35968 2/20 0.36
SRC P12931 1/20 0.36
BRAF P15056 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29481010 0.81 GRIA1 (0.47) PTGS2MAPK14FLT3ALDH1A1NPC1
SCHEMBL29068429 0.81 PTGS2 (0.72) PTGS2
SCHEMBL27715107 0.76 PTGS2 (0.64) PTGS2MAPK14FLT3ALDH1A1NPC1
SCHEMBL4592735 0.74 PTGS2 (0.53) PTGS2FLT3NPC1RAB9ASMN1; SMN2
SCHEMBL6180422 0.72 HSP90AA1 (0.44) PTGS2FLT3
SCHEMBL4918482 0.71 MAPK14 (0.67) MAPK14
SCHEMBL5698464 0.70 MAPK14 (0.44) PTGS2MAPK14FLT3ALDH1A1
SCHEMBL8488021 0.70 PTGS1 (0.45) PTGS2MAPK14NPC1MAPTRAB9A
SCHEMBL6930155 0.70 MAPK14 (0.67) MAPK14
SCHEMBL7354157 0.70 MAPK14 (0.67) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250311689-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-09 US claimed
WO-2023056236-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-04-06 WO claimed
CN-105039258-A Method and composition used for obtaining neuron-like cells from non-neuronal cells via reprogramming UNIV BEIJING 2015-11-11 CN claimed
US-20250311689-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2025-10-09 US disclosed
WO-2023056236-A1 SEEDLING GERMINATION AND GROWTH CONDITIONS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-04-06 WO disclosed
CN-105039258-A Method and composition used for obtaining neuron-like cells from non-neuronal cells via reprogramming UNIV BEIJING 2015-11-11 CN disclosed