SCHEMBL29068429

SCHEMBL29068429

CS(=O)(=O)c1ccc(-c2ncc(-c3ccncc3)n2-c2ccc(F)cc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 17/20 0.72
PTGS1 P23219 4/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293890 0.84 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL29481010 0.81 GRIA1 (0.47) PTGS2
SCHEMBL28037084 0.81 PTGS2 (0.46) PTGS2
SCHEMBL8800251 0.80 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL6289831 0.80 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL6289850 0.80 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL8801440 0.78 PTGS2 (0.71) PTGS2PTGS1
SCHEMBL6291259 0.78 PTGS2 (0.71) PTGS2PTGS1
SCHEMBL6291101 0.77 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL6293745 0.77 PTGS2 (0.70) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116744947-A Method for producing regenerated T cells through iPS cells 赛雅思株式会社 2023-09-12 CN disclosed
CN-115698270-A Method for producing regenerative T cells through iPS cells 赛雅思株式会社 2023-02-03 CN disclosed