Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504545 | 0.83 | BACE1 (0.48) | AHRBACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28047821 | 0.78 | AHR (0.42) | AHRBACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29275236 | 0.77 | AHR (0.49) | AHRBACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30961606 | 0.77 | AHR (0.49) | AHRBACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3300303 | 0.76 | TAAR1 (0.60) | SLC6A3DAOTAAR1 | |
| SCHEMBL28036822 | 0.76 | QPCTL (0.40) | DAOTAAR1DBHHTR2CHTR2B | |
| SCHEMBL2277951 | 0.76 | KDM4E (0.62) | BACE1NLRP3ENPP2 | |
| SCHEMBL28047882 | 0.75 | MKNK1 (0.55) | — | |
| SCHEMBL2279450 | 0.75 | KMT2A (0.49) | BACE1NLRP3 | |
| SCHEMBL7087919 | 0.75 | AHR (0.63) | AHRBACE1GPR84ENPP2CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189481-A | Pyridine cdk9 kinase inhibitors | ABBVIE INC | 2015-12-23 | — | — | CN | disclosed |
| CN-105026393-A | Cdk9 kinase inhibitors | ABBVIE INC | 2015-11-04 | — | — | CN | disclosed |