Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29854164 | 0.83 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL4946642 | 0.83 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL28267775 | 0.81 | LMNA (0.44) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL14477064 | 0.80 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL1515202 | 0.80 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL27974640 | 0.80 | LMNA (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL2485031 | 0.80 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL7751257 | 0.79 | CHRNB2 (0.45) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL11911979 | 0.77 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA | |
| SCHEMBL12549630 | 0.77 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNB4CHRNA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099898-A | compound and use thereof | 优曼尼蒂治疗公司 | 2019-08-06 | — | — | CN | disclosed |
| CN-105153020-A | Preparation method for aromatic azide | Hunan huateng pharmaceutical co ltd | 2015-12-16 | — | — | CN | disclosed |