Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917680 | 0.82 | KMT2A (0.31) | SMN1; SMN2HPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL7639692 | 0.78 | USP2 (0.37) | LMNAPOLBUSP2SMN1; SMN2HPGD | |
| SCHEMBL12089502 | 0.72 | PDE8B (0.36) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL8860611 | 0.72 | PDE8B (0.36) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL19193766 | 0.72 | USP2 (0.35) | LMNAPOLBUSP2SMN1; SMN2HPGD | |
| SCHEMBL12090067 | 0.72 | PDE8B (0.36) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL22145206 | 0.72 | USP2 (0.40) | LMNAPOLBUSP2SMN1; SMN2HPGD | |
| SCHEMBL29018459 | 0.72 | USP2 (0.40) | LMNAPOLBUSP2SMN1; SMN2HPGD | |
| SCHEMBL797696 | 0.71 | PDE8B (0.35) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL6137050 | 0.71 | USP2 (0.35) | LMNAPOLBUSP2SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105037335-A | Preparation method for 2,7'-di(4-pyridyl)-9-(15-crown-4)fluorene ligand | XIONG LILI | 2015-11-11 | — | — | CN | disclosed |