Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PDE8B | O95263 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037271 | 0.82 | LMNA (0.33) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10379970 | 0.73 | USP2 (0.35) | KMT2AMEN1PDE8BALDH1A1KDM4E | |
| SCHEMBL18833108 | 0.72 | NOS1 (0.36) | KMT2AMEN1HPGDSMN1; SMN2 | |
| SCHEMBL7639692 | 0.72 | USP2 (0.37) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL12089502 | 0.71 | PDE8B (0.36) | KMT2AMEN1PDE8BALDH1A1KDM4E | |
| SCHEMBL8860611 | 0.71 | PDE8B (0.36) | KMT2AMEN1PDE8BALDH1A1KDM4E | |
| SCHEMBL12090067 | 0.71 | PDE8B (0.36) | KMT2AMEN1PDE8BALDH1A1KDM4E | |
| SCHEMBL18595249 | 0.71 | HTT (0.35) | KMT2AMEN1PDE8BHPGDSMN1; SMN2 | |
| SCHEMBL797696 | 0.70 | PDE8B (0.35) | KMT2AMEN1PDE8BALDH1A1KDM4E | |
| SCHEMBL13502926 | 0.69 | ANPEP (0.34) | PDE8BHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618938-A | Process for preparing stereo isomers of neurokinin receptor antagonists | SANOFI (FR) | 1997-04-08 | — | — | US | disclosed |