Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137050 | 0.80 | USP2 (0.35) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL8863690 | 0.79 | USP2 (0.37) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL23501590 | 0.79 | USP2 (0.37) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL28037271 | 0.78 | LMNA (0.33) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL11782848 | 0.78 | USP2 (0.36) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL22145206 | 0.77 | USP2 (0.40) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL29018459 | 0.77 | USP2 (0.40) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL8208318 | 0.76 | — | — | |
| SCHEMBL11025614 | 0.75 | USP2 (0.34) | USP2SMN1; SMN2HPGDTP53ALOX12 | |
| SCHEMBL4888352 | 0.75 | USP2 (0.41) | USP2SMN1; SMN2HPGDTP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472227-B1 | A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0457213-A2 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0373508-A2 | Barbiturate assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-06-20 | — | — | EP | disclosed |