Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23330163 | 0.85 | CARM1 (0.48) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28037413 | 0.84 | CARM1 (0.39) | CARM1PRMT6CHRM2CHRM1CHRM3 | |
| SCHEMBL28036947 | 0.83 | CARM1 (0.49) | CARM1PRMT6SIGMAR1TMEM97PRMT8 | |
| SCHEMBL20758455 | 0.82 | CARM1 (0.47) | CARM1PRMT6CHRM2CHRM1CHRM3 | |
| SCHEMBL28036953 | 0.82 | CARM1 (0.43) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28036949 | 0.81 | CARM1 (0.50) | CARM1PRMT6SIGMAR1DRD4TMEM97 | |
| SCHEMBL28265428 | 0.78 | GRIN2D (0.39) | CARM1PRMT6SIGMAR1KCNH2CACNA1I | |
| SCHEMBL28036951 | 0.76 | SLC6A4 (0.51) | CHRM2CHRM1CHRM3KCNH2 | |
| SCHEMBL28036941 | 0.73 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL28823220 | 0.72 | GPR119 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105153119-B | Pyridine pyrimidinamine compound or pyridine pyridyl amine compound and its application | 广州必贝特医药技术有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-105153119-A | Pyridylpyrimidyl amine compounds or pyridylpyridyl amine compounds and application thereof | GUANGZHOU KEQIN NEW MEDICINE DESIGN CO LTD | 2015-12-16 | — | — | CN | disclosed |