Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20456692 | 0.74 | CYP11B1 (0.35) | KDM4EAR | |
| SCHEMBL28037273 | 0.74 | KEAP1 (0.58) | GAANPC1RAB9ACHEK1F2RL3 | |
| SCHEMBL2579099 | 0.74 | CREBBP (0.45) | NPC1RAB9AKDM1AHSD11B1 | |
| SCHEMBL3418909 | 0.72 | KEAP1 (0.51) | KDM4ENPC1RAB9A | |
| SCHEMBL25302131 | 0.72 | MEN1 (0.44) | KDM4EKDM1AAR | |
| SCHEMBL30509992 | 0.72 | MEN1 (0.44) | KDM4EKDM1AAR | |
| SCHEMBL4503250 | 0.71 | PLAUR (0.55) | — | |
| SCHEMBL30510017 | 0.70 | CYP11B1 (0.41) | KDM4EKDM1AAR | |
| SCHEMBL25380379 | 0.70 | CYP11B1 (0.41) | KDM4EKDM1AAR | |
| SCHEMBL29152983 | 0.70 | KMT2A (0.47) | NPC1RAB9AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164124-A | Compounds and compositions for treating parasitic diseases | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |