Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | SCN4A | P35499 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807623 | 0.79 | GRM5 (0.58) | KMT2A | |
| SCHEMBL6852707 | 0.78 | KEAP1 (0.55) | KEAP1KMT2ACYP19A1SCN4ACHEK1 | |
| SCHEMBL26199262 | 0.76 | SCN4A (0.52) | KEAP1KMT2ACYP19A1SCN4ACYP11B2 | |
| SCHEMBL12319225 | 0.75 | KEAP1 (0.67) | KEAP1KMT2ACYP19A1SCN4AGAA | |
| SCHEMBL15885116 | 0.75 | CHEK1 (0.56) | KEAP1KMT2ACYP19A1SCN4ACHEK1 | |
| SCHEMBL28734542 | 0.75 | ALDH1A1 (0.48) | KMT2AGAACYP11B2CHEK1NPC1 | |
| SCHEMBL17090942 | 0.74 | CYP19A1 (0.50) | CYP19A1GAACYP11B2CHEK1F2RL3 | |
| SCHEMBL28037403 | 0.74 | GAA (0.41) | GAACHEK1F2RL3NPC1RAB9A | |
| SCHEMBL6847795 | 0.74 | KEAP1 (0.50) | KEAP1KMT2ACYP19A1SCN4ACHEK1 | |
| SCHEMBL15885670 | 0.74 | KEAP1 (0.64) | KEAP1KMT2ACYP19A1SCN4ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105164124-B | Compounds and compositions for treating parasitic diseases | 诺华股份有限公司 | 2017-03-15 | — | — | CN | disclosed |
| CN-105164124-A | Compounds and compositions for treating parasitic diseases | NOVARTIS AG | 2015-12-16 | — | — | CN | disclosed |