Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 9/20 | 0.54 |
| ▸ | MGAM | O43451 | 8/20 | 0.54 |
| ▸ | SI | P14410 | 8/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037868 | 0.90 | GAA (0.67) | KDRGAAMGAMSIMGAM2 | |
| SCHEMBL28037866 | 0.79 | GAA (0.68) | KDRGAAMGAMSIMGAM2 | |
| SCHEMBL28037533 | 0.77 | KDR (0.71) | KDRGAAMAPTHPGDALDH1A1 | |
| SCHEMBL9670927 | 0.71 | MAPT (0.72) | KDRGAAMGAMSIMGAM2 | |
| SCHEMBL9670924 | 0.71 | MAPT (0.72) | KDRGAAMGAMSIMGAM2 | |
| SCHEMBL17327747 | 0.71 | MAPT (0.77) | KDRGAAMAPTHPGDALDH1A1 | |
| SCHEMBL4390502 | 0.71 | MGAM (1.00) | GAAMGAMSIMGAM2 | |
| SCHEMBL28153425 | 0.69 | MAPT (0.73) | KDRMAPTHPGDALDH1A1KDM4E | |
| SCHEMBL14983765 | 0.68 | AR (0.76) | GAAMAPTKDM4EHTTKDM1A | |
| SCHEMBL2587845 | 0.66 | MAPT (0.57) | KDRMAPTHPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017197-A | Semicarbazone compound preparation method and application in biomedicine | UNIV HUAZHONG NORMAL | 2015-11-04 | — | — | CN | disclosed |