Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | NT5E | P21589 | 2/20 | 0.66 |
| ▸ | CA12 | O43570 | 4/20 | 0.64 |
| ▸ | CA9 | Q16790 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670924 | 1.00 | MAPT (0.72) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL28153425 | 0.85 | MAPT (0.73) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL17327747 | 0.84 | MAPT (0.77) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL28037533 | 0.83 | KDR (0.71) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL10362370 | 0.82 | ALDH1A1 (0.61) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL10362373 | 0.82 | ALDH1A1 (0.61) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL31152434 | 0.82 | MAPT (1.00) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL9670246 | 0.82 | MAPT (0.68) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL9670243 | 0.82 | MAPT (0.68) | MAPTHPGDKDM4EALDH1A1HTT | |
| SCHEMBL8298413 | 0.80 | MAOB (0.69) | MAPTHPGDKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | claimed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | claimed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | claimed |
| EP-0299973-B1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0299973-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS. | UPJOHN CO (US) | 1989-01-25 | — | — | EP | disclosed |
| WO-1987006133-A1 | ANTHELMINTIC ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-10-22 | — | — | WO | disclosed |