Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NT5E | P21589 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28153425 | 0.84 | MAPT (0.73) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL9670924 | 0.83 | MAPT (0.72) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL9670927 | 0.83 | MAPT (0.72) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL28037868 | 0.81 | GAA (0.67) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL28037866 | 0.79 | GAA (0.68) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL17327747 | 0.78 | MAPT (0.77) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL28037531 | 0.77 | KDR (0.55) | KDRMAPTALDH1A1HPGDKDM4E | |
| SCHEMBL8298413 | 0.77 | MAOB (0.69) | MAPTALDH1A1HPGDKDM4EHTT | |
| SCHEMBL31152434 | 0.76 | MAPT (1.00) | MAPTALDH1A1HPGDKDM4EHTT | |
| SCHEMBL9668560 | 0.76 | CA12 (0.67) | MAPTALDH1A1HPGDKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017197-A | Semicarbazone compound preparation method and application in biomedicine | UNIV HUAZHONG NORMAL | 2015-11-04 | — | — | CN | disclosed |