Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | GRK5 | P34947 | 2/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | PRKX | P51817 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804664 | 0.77 | RET (0.44) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL11679338 | 0.72 | RET (0.61) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL29689422 | 0.70 | RET (0.46) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL9179277 | 0.69 | RET (0.53) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL2802516 | 0.67 | RET (0.41) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL9617271 | 0.65 | CA12 (0.37) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL11677692 | 0.65 | CA12 (0.54) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL18726067 | 0.64 | CA12 (0.41) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL13931179 | 0.63 | CA12 (0.61) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL3984666 | 0.61 | RET (1.00) | RETGRK5TYRO3DYRK1BCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260050-B1 | IMPROVED SUCRALOSE PURIFICATION PROCESS | TATE & LYLE TECHNOLOGY LTD (GB) | 2014-09-17 | — | — | EP | disclosed |
| US-8497367-B2 | Sucralose purification process | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2013-07-30 | — | — | US | disclosed |
| EP-2260050-A1 | IMPROVED SUCRALOSE PURIFICATION PROCESS | Tate & Lyle Technology Limited (GB) | 2010-12-15 | — | — | EP | disclosed |
| US-20090299054-A1 | SUCRALOSE PURIFICATION PROCESS | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
| WO-2009124116-A1 | IMPROVED SUCRALOSE PURIFICATION PROCESS | TATE & LYLE TECHNOLOGY LTD (GB) | 2009-10-08 | — | — | WO | disclosed |