Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | GRK5 | P34947 | 2/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2803756 | 0.67 | RET (0.44) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL2804664 | 0.63 | RET (0.44) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL7279275 | 0.61 | CA12 (0.52) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL369310 | 0.61 | UCHL1 (0.43) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| SCHEMBL29414113 | 0.61 | UCHL1 (0.43) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| SCHEMBL29202777 | 0.59 | UCHL1 (0.41) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| SCHEMBL1725776 | 0.58 | RET (1.00) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL12261815 | 0.57 | RET (0.51) | RETGRK5TYRO3DYRK1BCHEK1 | |
| Ethane SCHEMBL29094893 | 0.57 | UCHL1 (0.39) | UCHL1UCHL3ECE1MUS81ALDH1A1 | |
| Ethylene SCHEMBL16860555 | 0.57 | UCHL1 (0.39) | UCHL1UCHL3ECE1MUS81ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260049-B1 | EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCY | TATE & LYLE TECHNOLOGY LTD (GB) | 2013-02-27 | — | — | EP | claimed |
| EP-2260050-B1 | IMPROVED SUCRALOSE PURIFICATION PROCESS | TATE & LYLE TECHNOLOGY LTD (GB) | 2014-09-17 | — | — | EP | disclosed |
| US-8497367-B2 | Sucralose purification process | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2013-07-30 | — | — | US | disclosed |
| EP-2260049-B1 | EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCY | TATE & LYLE TECHNOLOGY LTD (GB) | 2013-02-27 | — | — | EP | disclosed |
| US-8212022-B2 | Effect of carbohydrate concentration on sucralose extraction efficiency | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2012-07-03 | — | — | US | disclosed |
| EP-2260049-A2 | EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCY | Tate & Lyle Technology Ltd (GB) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260050-A1 | IMPROVED SUCRALOSE PURIFICATION PROCESS | Tate & Lyle Technology Limited (GB) | 2010-12-15 | — | — | EP | disclosed |
| US-20100081803-A1 | EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCY | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2010-04-01 | — | — | US | disclosed |
| US-20090299055-A1 | Purification of Sucralose Containing Feed Streams for Sucralose Crystallization | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
| US-20090299054-A1 | SUCRALOSE PURIFICATION PROCESS | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-12-03 | — | — | US | disclosed |
| WO-2009146052-A2 | CRYSTALLIZATION OF SUCRALOSE FROM SUCRALOSE-CONTAINING FEED STREAMS | TATE & LYLE TECHNOLOGY LTD (GB) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009137193-A2 | EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCY | TATE & LYTE TECHNOLOGY LTD (GB) | 2009-11-12 | — | — | WO | disclosed |
| US-20090281295-A1 | CRYSTALLIZATION OF SUCRALOSE FROM SUCRALOSE-CONTAINING FEED STREAMS | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-11-12 | — | — | US | disclosed |
| WO-2009137192-A2 | PURIFICATION OF SUCRALOSE CONTAINING FEED STREAMS FOR SUCRALOSE CRYSTALLIZATION | TATE & LYLE TECHNOLOGY LTD (GB) | 2009-11-12 | — | — | WO | disclosed |
| US-20090259036-A1 | EXTRACTION OF LESS POLAR IMPURITIES FROM SUCRALOSE CONTAINING AQUEOUS FEED STREAMS | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-10-15 | — | — | US | disclosed |
| US-20090259036-A1 | EXTRACTION OF LESS POLAR IMPURITIES FROM SUCRALOSE CONTAINING AQUEOUS FEED STREAMS | TATE & LYLE TECHNOLOGY LIMITED (GB) | 2009-10-15 | — | — | US | disclosed |
| WO-2009124116-A1 | IMPROVED SUCRALOSE PURIFICATION PROCESS | TATE & LYLE TECHNOLOGY LTD (GB) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009124113-A1 | EXTRACTION OF LESS POLAR IMPURITIES FROM SUCRALOSE CONTAINING AQUEOUS FEED STREAMS | TATE & LYLE TECHNOLOGY LTD. (GB) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009124113-A1 | EXTRACTION OF LESS POLAR IMPURITIES FROM SUCRALOSE CONTAINING AQUEOUS FEED STREAMS | TATE & LYLE TECHNOLOGY LTD. (GB) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299055-A1 | Purification of Sucralose Containing Feed Streams for Sucralose Crystallization | SORD, SI, GYS2 | RET 2771/4885GRK5 4584/4885TYRO3 3842/4885 |
| US-20090259036-A1 | EXTRACTION OF LESS POLAR IMPURITIES FROM SUCRALOSE CONTAINING AQUEOUS FEED STREAMS | SI, SORD, SUCNR1 | RET 1923/4885GRK5 4465/4885TYRO3 2560/4885 |
| US-20100081803-A1 | EFFECT OF CARBOHYDRATE CONCENTRATION ON SUCRALOSE EXTRACTION EFFICIENCY | SI, SORD, SLC2A8 | RET 2284/4885GRK5 4608/4885TYRO3 3933/4885 |
| US-20090281295-A1 | CRYSTALLIZATION OF SUCRALOSE FROM SUCRALOSE-CONTAINING FEED STREAMS | SI, SORD, GYS2 | RET 2509/4885GRK5 3776/4885TYRO3 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.