Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5198386 | 0.83 | APAF1 (0.38) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL17292797 | 0.71 | PIK3C3 (0.32) | — | |
| SCHEMBL9508287 | 0.70 | MAPT (0.66) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL19440103 | 0.68 | MAPT (0.49) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL15672213 | 0.68 | MAPT (0.49) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL3631370 | 0.66 | MAPT (0.53) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL1821124 | 0.65 | MAPT (0.42) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL18104502 | 0.64 | MAPT (0.45) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL6129248 | 0.64 | MAPT (0.45) | KMT2AMEN1NPC1RAB9ATDP2 | |
| SCHEMBL4594682 | 0.64 | MAPT (0.41) | KMT2AMEN1NPC1RAB9ATDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051022-A | Process and intermediates for the preparation of pregabalin | PFIZER IRELAND PHARMACEUTICALS | 2015-11-11 | — | — | CN | disclosed |