SCHEMBL9508287

SCHEMBL9508287

O=C1C=C(N2CCOCC2)C(N2CCOCC2)=CC1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.66
HTT P42858 3/20 0.66
TP53 P04637 1/20 0.66
STAT3 P40763 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
KMT2A Q03164 5/20 0.59
MEN1 O00255 4/20 0.59
RAB9A P51151 4/20 0.59
LMNA P02545 3/20 0.59
NPC1 O15118 3/20 0.59
APAF1 O14727 2/20 0.59
TDP2 O95551 2/20 0.59
NSD2 O96028 2/20 0.59
GALK1 P51570 2/20 0.59
BLM P54132 2/20 0.59
HKDC1 Q2TB90 2/20 0.59
ATG4B Q9Y4P1 2/20 0.59
ATM Q13315 1/20 0.59
NOD2 Q9HC29 1/20 0.59
S100A4 P26447 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958544 0.82 DNMT1 (0.52) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL247037 0.77 KMT2A (0.79) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL4647391 0.76 APAF1 (1.00) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL30601628 0.76 APAF1 (1.00) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL15672213 0.74 MAPT (0.49) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL19440103 0.74 MAPT (0.49) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL7500812 0.73 MAPT (0.47) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL14566962 0.72 KMT2A (0.61) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL3631370 0.71 MAPT (0.53) MAPTHTTTP53STAT3SMN1; SMN2
SCHEMBL1676679 0.71 DNMT1 (0.52) MAPTHTTTP53STAT3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0404042-B1 INFRARED ABSORBING FERROUS COMPLEXES FOR DYE-DONOR ELEMENT USED IN LASER-INDUCED THERMAL DYE TRANSFER EASTMAN KODAK COMPANY (US) 1993-09-15 EP disclosed
EP-0404042-A1 Infrared absorbing ferrous complexes for dye-donor element used in laser-induced thermal dye transfer EASTMAN KODAK COMPANY (US) 1990-12-27 EP disclosed
US-4912083-A Dye containing azo group and morpholine and phenyl rings EASTMAN KODAK COMPANY (US) 1990-03-27 US disclosed
US-4892584-A METALLIZED AZO DYES EASTMAN KODAK COMPANY (US) 1990-01-09 US disclosed
EP-0070018-B1 PHOTOGRAPHIC ELEMENTS EMPLOYING NOVEL, NONDIFFUSIBLE 2-(2-PYRIDYLAZO)-4,5-BIS(TERTIARY AMINO)PHENOL BLACK DYE-RELEASING COMPOUNDS OR PRECURSORS THEREOF EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-10 EP disclosed
EP-0070018-A1 Photographic elements employing novel, nondiffusible 2-(2-pyridylazo)-4,5-bis(tertiary amino)phenol black dye-releasing compounds or precursors thereof EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-01-19 EP disclosed
US-4368153-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1983-01-11 US disclosed
US-4368248-A Photographic products and processes employing novel nondiffusible 2-(2-pyridylazo)-4,5-bis(tertiary amino)phenol black dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1983-01-11 US disclosed
US-4357411-A Photographic products and processes employing novel nondiffusible 2-(2-pyridylazo)-4,5-bis(tertiary amino)phenol black dye-releasing compounds and precursors thereof EASTMAN KODAK COMPANY (US) 1982-11-02 US disclosed