Fluoride

Fluoride

SCHEMBL28037720

CCCCCC=C(C)C(=O)OC(C)C.F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
EP300 Q09472 1/20 0.42
FAAH O00519 5/20 0.37
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29117916 0.98 LMNA (0.46) LMNAEP300FAAHALDH1A1MAPT
SCHEMBL7087960 0.93 LMNA (0.43) LMNAEP300FAAHALDH1A1CNR1
Acrylic Acid SCHEMBL28190282 0.89 EP300 (0.40) LMNAEP300FAAHHPGDTSHR
SCHEMBL28987152 0.86 LMNA (0.39) LMNAEP300FAAHALDH1A1MAPT
SCHEMBL27681486 0.85 TSHR (0.39) LMNAFAAHTSHR
SCHEMBL22576737 0.85 EP300 (0.44) LMNAEP300FAAHCNR1CNR2
SCHEMBL8615181 0.83 EP300 (0.40) LMNAEP300FAAH
SCHEMBL8615185 0.83 EP300 (0.40) LMNAEP300FAAH
SCHEMBL28273731 0.83 EP300 (0.46) LMNAEP300FAAHMAPT
SCHEMBL28493032 0.82 FAAH (0.55) LMNAEP300FAAHALDH1A1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105377811-A Cyanostilbenes ROLIC AG 2016-03-02 CN disclosed