SCHEMBL28037840

SCHEMBL28037840

Cc1ccc(C(O)F)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
CHRNA7 P36544 1/20 0.44
ALOX5 P09917 1/20 0.38
LMNA P02545 3/20 0.36
ALDH1A1 P00352 3/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
CA2 P00918 1/20 0.36
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
MLKL Q8NB16 1/20 0.35
MAPT P10636 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9732281 0.79 CHRNA7 (0.46) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL17020102 0.79 CHRNA7 (0.46) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL11938483 0.77 CHRNA7 (0.55) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL3693273 0.77 CHRNA7 (0.55) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL2055581 0.77 ACHE (0.50) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL371162 0.77 ACHE (0.50) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL96180 0.77 ACHE (0.50) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL44352 0.77 ACHE (0.50) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL11938485 0.77 CHRNA7 (0.55) ACHETDP1CHRNA7ALOX5LMNA
SCHEMBL31621802 0.75 CHRNA7 (0.38) ACHETDP1CHRNA7ALOX5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384669-A A kind of pyrethroid compound and its synthetic method and application 江苏扬农化工股份有限公司 2019-02-26 CN claimed
CN-105063833-A Short fiber composite spinning device and spinning method thereof NINGXIA RONGCHANG CASHMERE GROUP CO LTD 2015-11-18 CN claimed
CN-109384669-A A kind of pyrethroid compound and its synthetic method and application 江苏扬农化工股份有限公司 2019-02-26 CN disclosed
CN-109384669-A A kind of pyrethroid compound and its synthetic method and application 江苏扬农化工股份有限公司 2019-02-26 CN disclosed
CN-105063833-A Short fiber composite spinning device and spinning method thereof NINGXIA RONGCHANG CASHMERE GROUP CO LTD 2015-11-18 CN disclosed