Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29699724 | 0.97 | ACHE (0.47) | ACHETDP1CHRNA7MLKLKMT2A | |
| SCHEMBL24562816 | 0.89 | LMNA (0.43) | ACHETDP1CHRNA7MLKLKMT2A | |
| SCHEMBL477385 | 0.89 | LMNA (0.50) | ACHEMLKLKMT2ALMNATSHR | |
| SCHEMBL477533 | 0.89 | LMNA (0.50) | ACHEMLKLKMT2ALMNATSHR | |
| SCHEMBL11419617 | 0.89 | ACHE (0.65) | ACHETDP1CHRNA7BRD4LMNA | |
| SCHEMBL477590 | 0.89 | LMNA (0.50) | ACHEMLKLKMT2ALMNATSHR | |
| SCHEMBL30910858 | 0.87 | CES2 (0.50) | TDP1MLKLBRD4LMNATSHR | |
| SCHEMBL21831189 | 0.87 | ACHE (0.62) | ACHETDP1CHRNA7MLKLKMT2A | |
| SCHEMBL5351433 | 0.87 | ALDH1A1 (0.62) | ACHETDP1CHRNA7MLKLKMT2A | |
| SCHEMBL12981660 | 0.87 | ACHE (0.62) | ACHETDP1CHRNA7MLKLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136381-B1 | POLYOLEFIN COMPOSITIONS | MILLIKEN RESEARCH CORPORATION (US) | 1988-06-08 | — | — | EP | claimed |
| US-4431497-A | CARBO ALCOHOLS, ETHERS AND ESTERS AS STABILIZERS; STERILIZATION OF FOOD AND MEDICAL EQUIPMENT PACKAGES; DISCOLORATION INHIBITION | MILLIKEN RESEARCH CORPORATION (US) | 1984-02-14 | — | — | US | claimed |
| JP-1038455-A | — | — | None | — | — | JP | disclosed |
| EP-4583876-A1 | COMBINATION OF A T CELL THERAPY AND CONTINUOUS OR INTERMITTENT DGK INHIBITOR DOSING | Juno Therapeutics, Inc. (US) | 2025-07-16 | — | — | EP | disclosed |
| CN-120152717-A | Combination of T cell therapy and continuous or intermittent DGK inhibitor administration | 朱诺治疗学股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025059098-A2 | PHOTOCATALYTIC CARBOXYLATION OF SUBSTRATES WITH CARBON OXIDE | NEW IRIDIUM INC. (US) | 2025-03-20 | — | — | WO | disclosed |
| CN-112654621-B | Substituted naphthyridinone compounds useful as T cell activators | 百时美施贵宝公司 | 2024-05-14 | — | — | CN | disclosed |
| US-20240108654-A1 | COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR | JUNO THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | US | disclosed |
| WO-2024054944-A1 | COMBINATION OF A T CELL THERAPY AND CONTINUOUS OR INTERMITTENT DGK INHIBITOR DOSING | JUNO THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| CN-117693508-A | Combination of T cell therapy and DGK inhibitors | 朱诺治疗学股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| EP-4301755-A1 | COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR | Juno Therapeutics, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| EP-0252162-A1 | PROCESS FOR PREPARING 2-UNSUBSTITUTED IMIDAZOLES | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-01-13 | — | — | EP | disclosed |
| EP-0231850-A2 | Process for the formation of high contrast negative images and silver halide photographic element | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |
| US-4603145-A | Antiatherosclerotic diphenyl alkanamides | AMERICAN CYANAMID COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| US-4536346-A | TREATMENT OF ATHEROSCLEROSIS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| EP-0124791-A1 | Aralkanamidophenyl compounds | AMERICAN CYANAMID COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |
| US-4431497-A | CARBO ALCOHOLS, ETHERS AND ESTERS AS STABILIZERS; STERILIZATION OF FOOD AND MEDICAL EQUIPMENT PACKAGES; DISCOLORATION INHIBITION | MILLIKEN RESEARCH CORPORATION (US) | 1984-02-14 | — | — | US | disclosed |
| US-4138488-A | Diphenylmethyl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-3957434-A | POLYAMIDES, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| JP-S06438455-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108654-A1 | COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR | DGKG, DGKA, DGKI | ACHE 3607/4885TDP1 1911/4885CHRNA7 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.