Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.72 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10203243 | 0.88 | CYP2C19 (0.68) | EPHX2CD274CYP2C19CYP2C9POLB | |
| SCHEMBL2679794 | 0.88 | LMNA (0.61) | EPHX2CD274POLBSMN1; SMN2LMNA | |
| SCHEMBL17554165 | 0.88 | BCL3 (0.71) | EPHX2CD274POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30560519 | 0.88 | BCL3 (0.71) | EPHX2CD274POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL29658300 | 0.87 | POLB (0.64) | EPHX2CD274POLBALDH1A1 | |
| SCHEMBL11479065 | 0.86 | CD274 (0.93) | EPHX2CD274POLBALDH1A1HPGD | |
| SCHEMBL29584690 | 0.84 | CYP2C19 (0.69) | EPHX2CD274CYP2C19CYP2C9POLB | |
| SCHEMBL9312796 | 0.83 | CYP2C19 (0.70) | EPHX2CD274CYP2C19CYP2C9POLB | |
| SCHEMBL9312802 | 0.83 | CYP2C19 (0.71) | EPHX2CD274CYP2C19CYP2C9POLB | |
| SCHEMBL29658344 | 0.82 | CD274 (0.66) | EPHX2CD274CYP2C19POLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105073725-A | Pyrazolyl-ureas as kinase inhibitors | RESPIVERT LTD | 2015-11-18 | — | — | CN | disclosed |