Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037625 | 0.90 | GAA (0.45) | GAARECQLNPC1RAB9ASMYD3 | |
| SCHEMBL28037867 | 0.75 | GAA (0.51) | GAARECQLNPC1RAB9ASMYD3 | |
| SCHEMBL28037624 | 0.72 | GAA (0.54) | GAARECQLNPC1RAB9ASMYD3 | |
| SCHEMBL28037870 | 0.72 | GAA (0.50) | GAARECQLNPC1RAB9ASMYD3 | |
| SCHEMBL13938473 | 0.62 | NPC1 (0.46) | GAARECQLNPC1RAB9ASMYD3 | |
| SCHEMBL21490105 | 0.60 | SMYD3 (0.60) | SMYD3 | |
| SCHEMBL5201218 | 0.59 | SMYD3 (0.44) | GAARECQLNPC1RAB9ASMYD3 | |
| SCHEMBL23575953 | 0.59 | SMYD3 (0.70) | NPC1RAB9ASMYD3L3MBTL1MAPT | |
| SCHEMBL19701378 | 0.59 | SMYD3 (0.70) | NPC1RAB9ASMYD3L3MBTL1MAPT | |
| SCHEMBL23576033 | 0.55 | SMYD3 (1.00) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017197-A | Semicarbazone compound preparation method and application in biomedicine | UNIV HUAZHONG NORMAL | 2015-11-04 | — | — | CN | disclosed |