Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037867 | 0.86 | GAA (0.51) | GAARECQLRAB9ANPC1MAPT | |
| SCHEMBL28037624 | 0.83 | GAA (0.54) | GAARECQLRAB9ANPC1MAPT | |
| SCHEMBL28037869 | 0.72 | GAA (0.44) | GAARECQLRAB9ANPC1MAPT | |
| SCHEMBL16701389 | 0.68 | NPSR1 (0.50) | GAARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL8223149 | 0.68 | NPSR1 (0.50) | GAARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL16701390 | 0.68 | NPSR1 (0.50) | GAARAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL28037625 | 0.68 | GAA (0.45) | GAARECQLRAB9ANPC1MAPT | |
| SCHEMBL13938473 | 0.67 | NPC1 (0.46) | GAARECQLRAB9ANPC1MAPT | |
| SCHEMBL1642339 | 0.65 | NPSR1 (0.44) | GAAMAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL20776950 | 0.65 | NPSR1 (0.44) | GAAMAPTALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017197-B | A kind of preparation method of semicarbazone class compound and the application in biomedical aspect | 华中师范大学 | 2017-07-07 | — | — | CN | disclosed |
| CN-105017197-A | Semicarbazone compound preparation method and application in biomedicine | UNIV HUAZHONG NORMAL | 2015-11-04 | — | — | CN | disclosed |