Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037624 | 0.89 | GAA (0.54) | GAARECQLRAB9ANPC1SMYD3 | |
| SCHEMBL28037870 | 0.86 | GAA (0.50) | GAARECQLRAB9ANPC1SMYD3 | |
| SCHEMBL28037869 | 0.75 | GAA (0.44) | GAARECQLRAB9ANPC1SMYD3 | |
| SCHEMBL28037625 | 0.71 | GAA (0.45) | GAARECQLRAB9ANPC1SMYD3 | |
| SCHEMBL13938473 | 0.68 | NPC1 (0.46) | GAARECQLRAB9ANPC1SMYD3 | |
| SCHEMBL5201218 | 0.68 | SMYD3 (0.44) | GAARECQLRAB9ANPC1SMYD3 | |
| SCHEMBL1641313 | 0.64 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL2024987 | 0.62 | ALDH1A1 (0.46) | RAB9ANPC1MAPTL3MBTL1KMT2A | |
| SCHEMBL2024988 | 0.62 | ALDH1A1 (0.46) | RAB9ANPC1MAPTL3MBTL1KMT2A | |
| SCHEMBL29934249 | 0.60 | METTL3 (0.42) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017197-A | Semicarbazone compound preparation method and application in biomedicine | UNIV HUAZHONG NORMAL | 2015-11-04 | — | — | CN | disclosed |