Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 2/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037911 | 0.94 | TYR (0.37) | TYRTP53TSHRHTR1DPLG | |
| SCHEMBL16245795 | 0.80 | LMNA (0.44) | TYRTP53TSHRHTTELANE | |
| SCHEMBL16245780 | 0.80 | LMNA (0.40) | TYRTP53TSHRALDH1A1GAA | |
| SCHEMBL28038241 | 0.79 | GABRA1 (0.44) | TP53TSHRALDH1A1LMNAPTGS1 | |
| SCHEMBL24845073 | 0.79 | TYR (0.40) | TYRTP53TSHRALDH1A1ALOX12 | |
| SCHEMBL1225696 | 0.79 | TYR (0.53) | TYRTP53TSHRPLGKLK1 | |
| SCHEMBL28037910 | 0.78 | TP53 (0.55) | TP53TSHRHTR1DPLGKLK1 | |
| SCHEMBL27557559 | 0.78 | TP53 (0.41) | TP53TSHRHTR1DELANE | |
| SCHEMBL28037937 | 0.77 | HTR1D (0.37) | TYRHTR1DPLGKLK1KLK6 | |
| SCHEMBL28038237 | 0.76 | TP53 (0.39) | TP53TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105189432-A | Improvements in or relating to organic compounds | GIVAUDAN SA | 2015-12-23 | — | — | CN | claimed |
| CN-105189432-A | Improvements in or relating to organic compounds | GIVAUDAN SA | 2015-12-23 | — | — | CN | disclosed |