SCHEMBL28037946

SCHEMBL28037946

C=CN1CCCC1=O.CCCCCC(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.33
BRD4 O60885 1/20 0.33
BRD2 P25440 1/20 0.33
PIK3CD O00329 1/20 0.32
LMNA P02545 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA13 Q8N1Q1 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
GAA P10253 1/20 0.31
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22973525 0.86 ALOX5 (0.42) ALOX5BRD4BRD2PIK3CDLMNA
Hexadecane SCHEMBL369966 0.86 ALOX5 (0.42) ALOX5BRD4BRD2PIK3CDLMNA
1-Pentanol SCHEMBL28649677 0.81 SMN1; SMN2 (0.38) ALOX5BRD4BRD2LMNACA12
SCHEMBL27601371 0.79 TSHR (0.48) ALOX5FAAHMGLL
SCHEMBL6229884 0.79 TSHR (0.48) ALOX5FAAHMGLL
SCHEMBL3674032 0.79 TSHR (0.48) ALOX5FAAHMGLL
SCHEMBL787107 0.79 TSHR (0.48) ALOX5FAAHMGLL
SCHEMBL786722 0.79 TSHR (0.48) ALOX5FAAHMGLL
Butyl Alcohol SCHEMBL28227812 0.79 ALDH1A1 (0.35) ALOX5BRD4BRD2PIK3CDLMNA
SCHEMBL27962943 0.78 ALOX5 (0.37) ALOX5GAAFAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105012227-A Antifungal composition for improving dissolution and preparation method thereof BEIJING JIMEITANG MEDICINE RES CO LTD 2015-11-04 CN disclosed